Does the MMR vaccine protect against monkeypox? The measles, mumps and rubella vaccine can protect against chicken pox, but not against monkey pox. The two diseases are caused by unrelated viruses: the orthopox virus for monkeypox and the varicella-zoster for chickenpox; so the likelihood of a vaccine for one disease giving you protection for the… Continue reading Does the Chicken Pox Vaccine Protect against Monkeypox?